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In particular generic 1000mg carafate with visa gastritis symptoms stomach pain, there has been an explosion of clinical trials in the past 50 years in neurology that has given our feld more treatments than ever before purchase carafate 1000 mg without prescription chronic gastritis lasts. T is explosion has also made it more difcult to start as a new neurologist and atempt to build expertise in evidence-based medicine from scratch purchase 1000mg carafate with amex gastritis reflux. Figuring out what to do for patients, and why to do it, is a never-ending process for all physi- cians, and it is particularly daunting for certain groups, such as the frst-year neu- rology resident who is making the transition from internship, or the new senior neurology resident who is atempting to lead a team for the very frst time. Even for the generalist who is beginning his or her frst practice, or the seasoned aca- demic specialist who fnds himself or herself bracing for a month on the ward ser- vice, feeling confdent in one’s knowledge base of foundational studies in clinical neurology is no easy task. No one book can provide what can only be acquired through years of reading and clinical experience. However, in the spirit of Oxford’s 50 Studies series, the purpose of this book is to provide an introduction to key clinical trials in neurol- ogy that have impacted practice. It is meant as a starting point, so that one may walk into rounds or a case conference and feel more confdent that they have an idea of why we do what we do. In fact, some of the papers summarized no longer represent our standard of care, but their initial impact on practice was dramatic enough that they are still shaping the narrative about how certain diseases are treated. Our hope is that the book will fll a need for trainees (and perhaps for practicing neurologists): a manual that places treat- ments for neurologic diseases into context and that allows one to drink from the fre hydrant that is clinical neurology perhaps a litle more easily. T e biggest issue with puting together a book such as this one is fguring out which 50 studies to include. While the selection of studies for this book were peer reviewed by a national commitee of educators in neurology, the botom line is that we picked studies that simply seem to come up on rounds frequently. Fair or not, we also emphasized subspecialties that happen to have a number of large multicenter clinical trials. One glance at the table of contents will reveal that the book is thus heavily weighted toward inpatient neurology and, in par- ticular, vascular neurology. T e fact that some subspecialties have much fewer studies represented is by no means a refection of their importance in neurology, but rather a recognition that, for beter or for worse, almost every neurologist is responsible for taking care of stroke patients because of their sheer prevalence on our services! As an initial volume, we consider this book a work in progress— we welcome your thoughts as to the studies that have been included or excluded, and believe that if the book has future editions, opportunities to refne its contents will exist. While starting a debate over which studies are most impactful is interesting, it is our wish that this book makes the foundations of evidence-based clinical neurol- ogy a litle less overwhelming to someone who is starting out. T anks very much for picking up this book; we very much hope that you fnd it useful. Many thanks for the hours of work that they put into writing and revising the chapters of this book. Michael Hochman, the 50 Studies series editor, and Oxford University Press for the opportunity to make this unique book a reality. Finally, we would like to thank the following reviewers, who were kind enough to spend time reviewing the content of this book.

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